ecogitar: NEUROBIOLOGY OF ADDICTION

domingo, 26 de outubro de 2008

NEUROBIOLOGY OF ADDICTION

Publisher: Elsevier's web site
By George Koob,

Molecular and Integrative Neurosciences Department , The Scripps Institute, La Jolla, California, USAMichel Le Moal, Physiopathologie du Comportement Institut National de la Sante et de la Recherche Medicale Universite Victor Segalen Bordeaux 2 Bordeaux, France

Description Neurobiology of Addiction is conceived as a current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction over the past 50 years. The book includes a scholarly introduction, thorough descriptions of animal models of addiction, and separate chapters on the neurobiological mechanisms of addiction for psychostimulants, opioids, alcohol, nicotine and cannabinoids. Key information is provided about the history, sources, and pharmacokinetics and psychopathology of addiction of each drug class, as well as the behavioral and neurobiological mechanism of action for each drug class at the molecular, cellular and neurocircuitry level of analysis. A chapter on neuroimaging and drug addiction provides a synthesis of exciting new data from neuroimaging in human addicts – a unique perspective unavailable from animal studies. The final chapters explore theories of addiction at the neurobiological and neuroadaptational level both from a historical and integrative perspective. The book incorporates diverse finding with an emphasis on integration and synthesis rather than discrepancies or differences in the literature.

How the Media Frames Political Issues

In The Emergence of American Political Issues (1977) McCombs and Shaw state that the most important effect of the mass media is "its ability to mentally order and organize our world for us. In short, the mass media may not be successful in telling us what to think, but they are stunningly successful in telling us what to think about."[13] The presidential observer Theodore White corroborates this conclusion in The Making of a President (1972):

The power of the press in America is a primordial one. It sets the agenda of public discussion; and this sweeping political power is unrestrained by any law. It determines what people will talk and think about - an authority that in other nations is reserved for tyrants, priests, parties and mandarins.[14]

McCombs and Shaw also note that the media's tendency to structure voters' perceptions of political reality in effect constitutes a bias: "to a considerable degree the art of politics in a democracy is the art of determining which issue dimensions are of major interest to the public or can be made salient in order to win public support."[15]

http://www.scottlondon.com/reports/frames.html